Intermittent and periodic fasting, longevity and disease
نویسندگان
چکیده
منابع مشابه
Impact of intermittent fasting on health and disease processes.
Humans in modern societies typically consume food at least three times daily, while laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns often leads to metabolic morbidities (insulin resistance, excessive accumulation of visceral fat, etc.), particularly when associated with a sedentary lifestyle. Because animals, including humans, evolved in environments whe...
متن کاملHealth Benefits of Islamic Intermittent Fasting
Background & Objective: Islamic fasting is observed by millions of Muslims across the world during the holy month of Ramadan and other specific days of the lunar year. Fasting Muslims abstain from eating and drinking from dawn until sunset. Depending on season and geographical location, Muslims maintain fasting for approximately 13-18 hours per day. The present study aimed to review the be...
متن کاملCardioprotective Effects of Intermittent Fasting
Calorie restriction, a dietary regimen reducing energy intake without causing malnutrition, prolongs lifespan and exerts medical and health benefits such as lowering metabolic risk factors for chronic diseases and ameliorating chronic conditions. Intermittent fasting (IF), a type of calorie restriction regimen, has attracted particular attention as it is cost-effective and more accessible while...
متن کاملPreventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
Huntington disease (HD) is caused by the expression of mutant huntingtin (mHTT) bearing a polyglutamine expansion. In HD, mHTT accumulation is accompanied by a dysfunction in basal autophagy, which manifests as specific defects in cargo loading during selective autophagy. Here we show that the expression of mHTT resistant to proteolysis at the caspase cleavage site D586 (C6R mHTT) increases aut...
متن کاملCardioprotection by intermittent fasting in rats.
BACKGROUND Intermittent fasting (IF), a dietary regimen in which food is available only every other day, increases the life span and reduces the incidence of age-associated diseases in rodents. We have reported neuroprotective effects of IF against ischemic injury of the brain. In this study, we examined the effects of IF on ischemic injury of the heart in rats. METHODS AND RESULTS After 3 mo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Aging
سال: 2021
ISSN: 2662-8465
DOI: 10.1038/s43587-020-00013-3